Publications

Top 5 Publications

PMID 41364508 (2025)

Physiological Normothermic Perfusion Enhances Kidney Preservation Versus the Established UK Normothermic Machine Perfusion Assessment Protocol. Stone JP, Norton W, Cowey WR, Milburn EL, Chesworth GE, Stewart AF, Bowers CJT, Ricci E, Entwistle TR, Amin K, Clancy M, Fildes JE. Kidney360. 2025 Dec 9. doi: 10.34067/KID.0000001055.

PMID 34043778 (2021)

Randomized preclinical study of machine perfusion in vascularized composite allografts. Amin KR, Stone JP, Kerr J, Geraghty A, Joseph L, Montero-Fernandez A, Wong JK, Fildes JE. Br J Surg. 2021 May 27;108(5):574-582. doi: 10.1002/bjs.11921.

PMID 26366523 (2016)

Altered Immunogenicity of Donor Lungs via Removal of Passenger Leukocytes Using Ex Vivo Lung Perfusion. Stone JP, Critchley WR, Major T, Rajan G, Risnes I, Scott H, Liao Q, Wohlfart B, Sjöberg T, Yonan N, Steen S, Fildes JE. Am J Transplant. 2016 Jan;16(1):33-43. doi: 10.1111/ajt.13446.

PMID 41092112 (2025)

Antioxidant Poly(propylene sulfide) Nanoparticles Ameliorate Ischemia-Reperfusion Injury and Improve Porcine Kidney Function Post-Transplantation. Stone JP, d'Arcy R, Geraghty A, Amin KR, Ghibaudi M, Francini N, Montero-Fernandez A, Dabare D, Ogliastro C, Sganga S, Coradello G, Rosa GD, Bramhall J, Galwey N, Ruseva M, Tirelli N, Fildes JE. ACS Appl Mater Interfaces. 2025 Oct 29;17(43):59067-59081. doi: 10.1021/acsami.5c11562.

PMID 28637880 (2017)

Study Comparing Vein Integrity and Clinical Outcomes in Open Vein Harvesting and 2 Types of Endoscopic Vein Harvesting for Coronary Artery Bypass Grafting: The VICO Randomized Clinical Trial. Krishnamoorthy B, Critchley WR, Thompson AJ, Payne K, Morris J, Venkateswaran RV, Caress AL, Fildes JE, Yonan N. Circulation. 2017 Oct 31;136(18):1688-1702. doi: 10.1161/CIRCULATIONAHA.117.028261.

Machine Perfusion & Organ Preservation

PMID 41364508 (2025)

PMID 38768518 (2024)

Developing an Injury-Free 15 Hour Preservation Protocol of Donor Porcine Kidneys Using Normothermic Machine Perfusion. Stone JP, Cowey WR, Bowers CJT, Stewart AF, Armstrong ER, Clancy M, Entwistle TR, Del Pozo J, Amin K, Fildes JE. ASAIO J. 2024 Dec 1;70(12):1067-1073. doi: 10.1097/MAT.0000000000002236.

PMID 34662442 (2022)

Renal hemofiltration prevents metabolic acidosis and reduces inflammation during normothermic machine perfusion of the vascularized composite allograft: A preclinical study. Stone JP, Amin KR, Geraghty A, Kerr J, Shaw M, Dabare D, Wong JK, Brough D, Entwistle TR, Montero-Fernandez A, Fildes JE. Artif Organs. 2022 Feb;46(2):259-272. doi: 10.1111/aor.14089.

PMID 34274245 (2021)

Normothermic ex vivo perfusion of the limb allograft depletes donor leukocytes prior to transplantation. Amin KR, Stone JP, Kerr JC, Wong JK, Fildes JE. J Plast Reconstr Aesthet Surg. 2021 Nov;74(11):2969-2976. doi: 10.1016/j.bjps.2021.03.071.

PMID 33264679 (2021)

A post-preservation vascular flush removes significant populations of donor leukocytes prior to lung transplantation. Ball AL, Edge RJ, Amin K, Critchley WR, Howell GJ, Yonan N, Stone JP, Fildes JE. Transpl Immunol. 2021 Feb;64:101356. doi: 10.1016/j.trim.2020.101356.

PMID 32502131 (2020)

Ex Vivo Lung Perfusion Improves the Inflammatory Signaling Profile of the Porcine Donor Lung Following Transplantation. Stone JP, Ball AL, Crichley W, Yonan N, Liao Q, Sjöberg T, Steen S, Fildes JE. Transplantation. 2020 Sep;104(9):1899-1905. doi: 10.1097/TP.0000000000003338.

PMID 29221684 (2018)

Ex-vivo flush of the limb allograft reduces inflammatory burden prior to transplantation. Amin KR, Ball AL, Chhina C, Edge RJ, Stone JP, Critchley WR, Wong JK, Fildes JE. J Plast Reconstr Aesthet Surg. 2018 Feb;71(2):140-146. doi: 10.1016/j.bjps.2017.11.002.

PMID 28551353 (2017)

The role of interleukin-1β as a predictive biomarker and potential therapeutic target during clinical ex vivo lung perfusion. Andreasson ASI, Borthwick LA, Gillespie C, Jiwa K, Scott J, Henderson P, Mayes J, Romano R, Roman M, Ali S, Fildes JE, Marczin N, Dark JH, Fisher AJ; DEVELOP-UK Investigators. J Heart Lung Transplant. 2017 Sep;36(9):985-995. doi: 10.1016/j.healun.2017.05.012.

PMID 29142927 (2016)

Ex Vivo Normothermic Perfusion Induces Donor-Derived Leukocyte Mobilization and Removal Prior to Renal Transplantation. Stone JP, Ball AL, Critchley WR, Major T, Edge RJ, Amin K, Clancy MJ, Fildes JE. Kidney Int Rep. 2016 Aug 6;1(4):230-239. doi: 10.1016/j.ekir.2016.07.009.

PMID 25757211 (2015)

Clinical Outcome of Patients Transplanted with Marginal Donor Lungs via Ex Vivo Lung Perfusion Compared to Standard Lung Transplantation. Fildes JE, Archer LD, Blaikley J, Ball AL, Stone JP, Sjöberg T, Steen S, Yonan N. Transplantation. 2015 May;99(5):1078-83. doi: 10.1097/TP.0000000000000462.

PMID 41092112 (2025)

PMID 35220355 (2022)

The Use of Hemoglobin-Based Oxygen Carriers in Ex Vivo Machine Perfusion of Donor Organs for Transplantation. Lodhi S, Stone JP, Entwistle TR, Fildes JE. ASAIO J. 2022 Apr 1;68(4):461-470. doi: 10.1097/MAT.0000000000001597.

PMID 35083252 (2022)

Hemodynamics and Metabolic Parameters in Normothermic Kidney Preservation Are Linked With Donor Factors, Perfusate Cells, and Cytokines. Weissenbacher A, Stone JP, Lo Faro ML, Hunter JP, Ploeg RJ, Coussios CC, Fildes JE, Friend PJ. Front Med (Lausanne). 2022 Jan 10;8:801098. doi: 10.3389/fmed.2021.801098.

PMID 34043778 (2021)

Randomized preclinical study of machine perfusion in vascularized composite allografts. Amin KR, Stone JP, Kerr J, Geraghty A, Joseph L, Montero-Fernandez A, Wong JK, Fildes JE. Br J Surg. 2021 May 27;108(5):574-582. doi: 10.1002/bjs.11921.

PMID 33264679 (2020)

Pro-IL-1β Is an Early Prognostic Indicator of Severe Donor Lung Injury During Ex Vivo Lung Perfusion. Major T, Ball AL, Stone JP, Edge RJ, Lopez-Castejon G, Sjöberg T, Andreasson A, Brough D, Steen S, Fisher AJ, Fildes JE. Transplantation. 2021 Apr 1;105(4):768-774. doi: 10.1097/TP.0000000000003463.

PMID 32849549 (2020)

Non-ischemic Heart Preservation via Hypothermic Cardioplegic Perfusion Induces Immunodepletion of Donor Hearts Resulting in Diminished Graft Infiltration Following Transplantation. Critchley WR, Stone JP, Liao Q, Qin G, Risnes I, Trafford A, Scott H, Sjöberg T, Steen S, Fildes JE. Front Immunol. 2020 Jul 28;11:1621. doi: 10.3389/fimmu.2020.01621.

PMID 29054354 (2017)

Strategies to Reduce Ischemia Reperfusion Injury in Vascularized Composite Allotransplantation of the Limb. Amin KR, Wong JKF, Fildes JE. J Hand Surg Am. 2017 Dec;42(12):1019-1024. doi: 10.1016/j.jhsa.2017.09.013.

PMID 28339927 (2017)

Characterizing the early inflammatory contribution of the donor kidney following reperfusion. Stone JP, Mohamud M, Amin K, Critchley WR, Edge RJ, Clancy MJ, Ball AL, Fildes JE. Nephrol Dial Transplant. 2017 Sep 1;32(9):1487-1492. doi: 10.1093/ndt/gfw464.

PMID 26366523 (2016)

PMID 25063532 (2014)

Mechanical removal of dendritic cell-generating non-classical monocytes via ex vivo lung perfusion. Stone JP, Sevenoaks H, Sjöberg T, Steen S, Yonan N, Fildes JE. J Heart Lung Transplant. 2014 Aug;33(8):864-9. doi: 10.1016/j.healun.2014.03.005.

Immunology

PMID 38518826 (2024)

The contribution of the donor vascularised hand and face allograft in transplant rejection: An immunological perspective. Amin KR, Fildes JE. Transpl Immunol. 2024 Jun;84:102035. doi: 10.1016/j.trim.2024.102035.

PMID 33582579 (2021)

Understanding immunological response to desensitisation strategies in highly sensitised potential kidney transplant patients. May FNJ, Rees MT, Griffin S, Fildes JE. Transplant Rev (Orlando). 2021 Apr;35(2):100596. doi: 10.1016/j.trre.2021.100596.

PMID 23653226 (2014)

Mucopolysaccharide diseases: a complex interplay between neuroinflammation, microglial activation and adaptive immunity. Archer LD, Langford-Smith KJ, Bigger BW, Fildes JE. J Inherit Metab Dis. 2014 Jan;37(1):1-12. doi: 10.1007/s10545-013-9613-3.

PMID 22260525 (2012)

Graft rejection - endogenous or allogeneic? Critchley WR, Fildes JE. Immunology. 2012 Jun;136(2):123-32. doi: 10.1111/j.1365-2567.2012.03560.x.

PMID 19746428 (2010)

Immune activation or immunomodulation in the brains of MPS IIIB mouse model. Archer LD, Langford K, Bigger B, Fildes JE. J Neurosci Res. 2010 Feb 1;88(2):233. doi: 10.1002/jnr.22211.

PMID 19386281 (2009)

Myocardial heat shock protein 60 expression is upregulated following acute cardiac rejection. Sarri S, Shaw SM, Gieschen-Krische MA, Archer L, Yonan N, Fildes JE. Transpl Immunol. 2009 Jul;21(3):140-2. doi: 10.1016/j.trim.2009.04.002.

PMID 19059118 (2008)

Mannose-binding lectin deficiency offers protection from acute graft rejection after heart transplantation. Fildes JE, Shaw SM, Walker AH, McAlindon M, Williams SG, Keevil BG, Yonan N. J Heart Lung Transplant. 2008 Dec;27(12):1353-6. doi: 10.1016/j.healun.2008.08.011.

PMID 18503891 (2008)

HMG-CoA reductase inhibitors deplete circulating classical and non-classical monocytes following human heart transplantation. Fildes JE, Shaw SM, Mitsidou A, Rogacev K, Leonard CT, Williams SG, Yonan N. Transpl Immunol. 2008 May;19(2):152-7. doi: 10.1016/j.trim.2008.02.002.

PMID 18267228 (2008)

Natural killer cells in peripheral blood and lung tissue are associated with chronic rejection after lung transplantation. Fildes JE, Yonan N, Tunstall K, Walker AH, Griffiths-Davies L, Bishop P, Leonard CT. J Heart Lung Transplant. 2008 Feb;27(2):203-7. doi: 10.1016/j.healun.2007.11.571.

PMID 17234526 (2007)

Large population sizes are a prerequisite for genetic association studies. Fildes JE, Williams SG, Yonan N. J Heart Lung Transplant. 2007 Jan;26(1):101. doi: 10.1016/j.healun.2006.11.001.

PMID 16387160 (2005)

The effects of ACE inhibition on serum angiotensin II concentration following cardiac transplantation. Fildes JE, Walker AH, Keevil B, Hutchinson IV, Leonard CT, Yonan N. Transplant Proc. 2005 Dec;37(10):4525-7. doi: 10.1016/j.transproceed.2005.10.099.

PMID 15964389 (2005)

Donor CCR5 Delta32 polymorphism and outcome following cardiac transplantation. Fildes JE, Walker AH, Howlett R, Bittar MN, Hutchinson IV, Leonard CT, Yonan N. Transplant Proc. 2005 Jun;37(5):2247-9. doi: 10.1016/j.transproceed.2005.03.101.

PMID 35599802 (2022)

Bionic Prostheses: The Emerging Alternative to Vascularised Composite Allotransplantation of the Limb. Amin KR, Fildes JE. Front Surg. 2022 May 6;9:873507. doi: 10.3389/fsurg.2022.873507.

PMID 28396194 (2017)

The use of kinase inhibitors in solid organ transplantation. Dholakia S, Fildes JE, Friend PJ. Transplant Rev (Orlando). 2017 Jul;31(3):166-171. doi: 10.1016/j.trre.2017.02.008.

PMID 22773246 (2012)

Characterisation of the T cell and dendritic cell repertoire in a murine model of mucopolysaccharidosis I (MPS I). Archer LD, Langford-Smith KJ, Critchley WR, Bigger BW, Fildes JE. J Inherit Metab Dis. 2013 Mar;36(2):257-62. doi: 10.1007/s10545-012-9508-8.

PMID 21332706 (2011)

Activated NK cells have a potential therapeutic role in sustaining donor engraftment following paediatric haematopoietic stem cell transplantation for non-malignant disease. Khan UA, Davidson JA, Poulton KV, Wynn RF, Fildes JE. Br J Haematol. 2011 Aug;154(4):527-9. doi: 10.1111/j.1365-2141.2010.08512.x.

PMID 19604298 (2009)

Melatonin - a pleiotropic molecule involved in pathophysiological processes following organ transplantation. Fildes JE, Yonan N, Keevil BG. Immunology. 2009 Aug;127(4):443-9. doi: 10.1111/j.1365-2567.2009.03113.x.

PMID 19332119 (2009)

Ezetimibe and atorvastatin both immunoregulate CD4+ T cells from cardiac transplant recipients in vitro. Shaw SM, Najam O, Khan U, Yonan N, Williams SG, Fildes JE. Transpl Immunol. 2009 Jul;21(3):179-82. doi: 10.1016/j.trim.2009.03.001.

PMID 18583135 (2008)

CMV infection is associated with the depletion but lack of activation of peripheral blood natural killer cells in a lung transplant cohort. Fildes JE, Walker AH, Williams SG, Yonan N, Leonard CT. Transpl Immunol. 2008 Jul;19(3-4):235-7. doi: 10.1016/j.trim.2008.05.007.

PMID 18346631 (2008)

Natural killer cells and lung transplantation, roles in rejection, infection, and tolerance. Fildes JE, Yonan N, Leonard CT. Transpl Immunol. 2008 Apr;19(1):1-11. doi: 10.1016/j.trim.2008.01.004.

PMID 18091511 (2007)

Does brain natriuretic peptide interact with the immune system after cardiac transplantation? Shaw SM, Fildes J, Yonan N, Williams SG. Transplantation. 2007 Dec 15;84(11):1377-81. doi: 10.1097/01.tp.0000295851.24889.bf.

PMID 17198259 (2006)

The MDR1/ABCB1 gene, a high-impact risk factor for cardiac transplant rejection. Barnard JB, Richardson S, Sheldon S, Fildes J, Pravica V, Hutchinson IV, Leonard CT, Yonan N. Transplantation. 2006 Dec 27;82(12):1677-82. doi: 10.1097/01.tp.0000250724.09996.bd.

PMID 15964393 (2005)

CD4-veCD8-ve CD30+ve T cells are detectable in human lung transplant patients and their proportion of the lymphocyte population after in vitro stimulation with donor spleen cells correlates with preservation of lung physiology. Polster K, Walker A, Fildes J, Entwistle G, Yonan N, Hutchinson IV, Leonard CT. Transplant Proc. 2005 Jun;37(5):2257-60. doi: 10.1016/j.transproceed.2005.03.114.

PMID 15797740 (2005)

Angiotensin converting enzyme insertion/deletion polymorphism does not influence postcardiac transplantation hypertension onset or progression. Fildes JE, Walker AH, Densem CG, Deiraniya AK, Hutchinson IV, Leonard CT, Yonan N. J Heart Lung Transplant. 2005 Apr;24(4):406-10. doi: 10.1016/j.healun.2003.11.407.

Clinical Trials & Surgical Techniques

PMID 33314283 (2021)

Modifying dietary patterns in cardiothoracic transplant patients to reduce cardiovascular risk: The AMEND-IT Trial. Entwistle TR, Miura K, Keevil BG, Morris J, Yonan N, Pohl M, Green AC, Fildes JE. Clin Transplant. 2021 Feb;35(2):e14186. doi: 10.1111/ctr.14186.

PMID 29444672 (2018)

Adherence to Mediterranean and low-fat diets among heart and lung transplant recipients: a randomized feasibility study. Entwistle TR, Green AC, Fildes JE, Miura K. Nutr J. 2018 Feb 14;17(1):22. doi: 10.1186/s12937-018-0337-y.

PMID 29016381 (2017)

Randomized Study Comparing the Effect of Carbon Dioxide Insufflation on Veins Using 2 Types of Endoscopic and Open Vein Harvesting. Krishnamoorthy B, Critchley WR, Nair J, Malagon I, Carey J, Barnard JB, Waterworth PD, Venkateswaran RV, Fildes JE, Caress AL, Yonan N. Innovations (Phila). 2017 Sep/Oct;12(5):320-328. doi: 10.1097/IMI.0000000000000405.

PMID 25415312 (2015)

Does the introduction of a comprehensive structured training programme for endoscopic vein harvesting improve conduit quality? A multicentre pilot study. Krishnamoorthy B, Critchley WR, Bhinda P, Crockett J, John A, Bridgewater BJ, Waterworth PD, Fildes J, Yonan N. Interact Cardiovasc Thorac Surg. 2015 Feb;20(2):186-93. doi: 10.1093/icvts/ivu354.

PMID 23939194 (2014)

Therapeutic drug monitoring of ciclosporin A and tacrolimus in heart lung transplant patients using dried blood spots. Hinchliffe E, Adaway J, Fildes J, Rowan A, Keevil BG. Ann Clin Biochem. 2014 Jan;51(Pt 1):106-9. doi: 10.1177/0004563213488759.

PMID 22397987 (2012)

Closed suction drainage improves clinical outcome in patients undergoing endoscopic vein harvesting for coronary artery bypass grafting. Krishnamoorthy B, Al-Fagih OS, Madi MI, Najam O, Waterworth PD, Fildes JE, Yonan N. Ann Thorac Surg. 2012 Apr;93(4):1201-5. doi: 10.1016/j.athoracsur.2011.12.060.

PMID 19696051 (2010)

A comparative analysis of saphenous vein conduit harvesting techniques for coronary artery bypass grafting--standard bridging versus the open technique. Khan UA, Krishnamoorthy B, Najam O, Waterworth P, Fildes JE, Yonan N. Interact Cardiovasc Thorac Surg. 2010 Jan;10(1):27-31. doi: 10.1510/icvts.2009.209171.

PMID 19295325 (2009)

The efficacy and tolerability of ezetimibe in cardiac transplant recipients taking cyclosporin. Shaw SM, Chaggar P, Ritchie J, Shah MK, Baynes AC, O'Neill N, Fildes JE, Yonan N, Williams SG. Transplantation. 2009 Mar 15;87(5):771-5. doi: 10.1097/TP.0b013e318198d7d0.

PMID 16183563 (2005)

Interleukin 6 G-174C polymorphism influences outcome following coronary revascularization surgery. Bittar MN, Carey JA, Barnard J, Fildes JE, Pravica V, Yonan N, Hutchinson IV. Heart Surg Forum. 2005;8(3):E140-5. doi: 10.1532/HSF98.20041120.

PMID 15686713 (2004)

The influence of donor age on transplant coronary artery disease and survival post heart transplantation: is it safe to extend donor age? Walker AH, Fildes JE, Leonard CT, Yonan N. Transplant Proc. 2004 Dec;36(10):3139-41. doi: 10.1016/j.transproceed.2004.12.007.

PMID 30529157 (2019)

A Randomized Study Comparing the Incidence of Postoperative Pain After Phrenic Nerve Infiltration Vs Nonphrenic Nerve Infiltration During Thoracotomy. Krishnamoorthy B, Critchley WR, Soon SY, Birla R, Begum Z, Nair J, Devan N, Mohan R, Fildes J, Morris J, Fullwood C, Krysiak P, Malagon I, Shah R. Semin Thorac Cardiovasc Surg. 2019 Autumn;31(3):583-592. doi: 10.1053/j.semtcvs.2018.11.014.

PMID 28637880 (2017)

PMID 26590381 (2016)

A randomized study comparing traditional monofilament knotted sutures with barbed knotless sutures for donor leg wound closure in coronary artery bypass surgery. Krishnamoorthy B, Shepherd N, Critchley WR, Nair J, Devan N, Nasir A, Barnard JB, Venkateswaran RV, Waterworth PD, Fildes JE, Yonan N. Interact Cardiovasc Thorac Surg. 2016 Feb;22(2):161-7. doi: 10.1093/icvts/ivv314.

PMID 25355663 (2015)

Histological and immunohistochemical evaluation of human saphenous vein harvested by endoscopic and open conventional methods. Hashmi SF, Krishnamoorthy B, Critchley WR, Walker P, Bishop PW, Venkateswaran RV, Fildes JE, Yonan N. Interact Cardiovasc Thorac Surg. 2015 Feb;20(2):178-85. doi: 10.1093/icvts/ivu359.

PMID 22611182 (2012)

A randomized study comparing three groups of vein harvesting methods for coronary artery bypass grafting: endoscopic harvest versus standard bridging and open techniques. Krishnamoorthy B, Critchley WR, Glover AT, Nair J, Jones MT, Waterworth PD, Fildes JE, Yonan N. Interact Cardiovasc Thorac Surg. 2012 Aug;15(2):224-8. doi: 10.1093/icvts/ivs164.

PMID 21801935 (2011)

Scrotal distension after endoscopic harvesting of the saphenous vein in patients with inguinal hernia. Najam O, Krishnamoorthy B, Kadir I, Karagounis AP, Waterworth P, Fildes JE, Yonan N. Ann Thorac Surg. 2011 Aug;92(2):733-5. doi: 10.1016/j.athoracsur.2011.01.098.

PMID 19853089 (2009)

Randomized prospective study comparing conventional subcuticular skin closure with Dermabond skin glue after saphenous vein harvesting. Krishnamoorthy B, Najam O, Khan UA, Waterworth P, Fildes JE, Yonan N. Ann Thorac Surg. 2009 Nov;88(5):1445-9. doi: 10.1016/j.athoracsur.2009.06.047.

PMID 19151171 (2009)

Liquid chromatography-mass spectrometry measurement of tacrolimus in finger-prick samples compared with venous whole blood samples. Keevil BG, Fildes J, Baynes A, Yonan N. Ann Clin Biochem. 2009 Mar;46(Pt 2):144-5. doi: 10.1258/acb.2008.008147.

PMID 15653385 (2005)

Changes in induced sputum in the presence of bronchiolitis obliterans syndrome and correlation with spirometry in single and bilateral lung transplant recipients. Allen DJ, Fildes JE, Yonan N, Leonard CT. J Heart Lung Transplant. 2005 Jan;24(1):88-91. doi: 10.1016/j.healun.2003.10.003.

Cardiovascular

PMID 32305466 (2021)

Substrate for the Myocardial Inflammation-Heart Failure Hypothesis Identified Using Novel USPIO Methodology. Lagan J, Naish JH, Simpson K, Zi M, Cartwright EJ, Foden P, Morris J, Clark D, Birchall L, Caldwell J, Trafford A, Fortune C, Cullen M, Chaudhuri N, Fildes J, Sarma J, Schelbert EB, Schmitt M, Piper Hanley K, Miller CA. JACC Cardiovasc Imaging. 2021 Feb;14(2):365-376. doi: 10.1016/j.jcmg.2020.02.001.

PMID 27297263 (2016)

Myocardial recovery with mechanical circulatory support. Chaggar PS, Williams SG, Yonan N, Fildes J, Venkateswaran R, Shaw SM. Eur J Heart Fail. 2016 Oct;18(10):1220-1227. doi: 10.1002/ejhf.575.

PMID 22138041 (2011)

Brain natriuretic peptide induces CD8+ T cell death via a caspase 3 associated pathway - implications following heart transplantation. Shaw SM, Critchley WR, Puchalka CM, Williams SG, Yonan N, Fildes JE. Transpl Immunol. 2012 Mar;26(2-3):119-22. doi: 10.1016/j.trim.2011.11.007.

PMID 19764947 (2009)

The pathophysiology of chronic graft failure in the cardiac transplant patient. Khan UA, Williams SG, Fildes JE, Shaw SM. Am J Transplant. 2009 Oct;9(10):2211-6. doi: 10.1111/j.1600-6143.2009.02807.x.

PMID 19619687 (2009)

The interpretation of clinical trial data - wrongly ACCLAIM'ed? Shaw SM, Yonan N, Williams SG, Fildes JE. Am Heart J. 2009 Aug;158(2):149-51. doi: 10.1016/j.ahj.2009.05.017.

PMID 19168508 (2009)

Immunological mechanisms of pentoxifylline in chronic heart failure. Shaw SM, Shah MK, Williams SG, Fildes JE. Eur J Heart Fail. 2009 Feb;11(2):113-8. doi: 10.1093/eurjhf/hfn040.

PMID 18577880 (2008)

Pleiotropic effects and cholesterol-lowering therapy. Shaw SM, Fildes JE, Yonan N, Williams SG. Cardiology. 2009;112(1):4-12. doi: 10.1159/000137692.

PMID 18523769 (2008)

Potential immunologic effects of statins in cancer following transplantation. Fildes JE, Shaw SM, Williams SG, Yonan N. Cancer Immunol Immunother. 2009 Mar;58(3):461-7. doi: 10.1007/s00262-008-0541-2.

PMID 29165554 (2017)

The effect of 1.5 T cardiac magnetic resonance on human circulating leucocytes. Critchley WR, Reid A, Morris J, Naish JH, Stone JP, Ball AL, Major T, Clark D, Waldron N, Fortune C, Lagan J, Lewis GA, Ainslie M, Schelbert EB, Davis DM, Schmitt M, Fildes JE, Miller CA. Eur Heart J. 2018 Jan 21;39(4):305-312. doi: 10.1093/eurheartj/ehx646.

PMID 23104250 (2013)

Heart rate after cardiac transplantation - lessons from the tortoise and the shrew. Critchley WR, Yonan N, Shaw SM, Fildes JE. Transplantation. 2013 Jan 27;95(2):259-65. doi: 10.1097/TP.0b013e31826bc42a.

PMID 19932747 (2010)

Can inflammation be an independent predictor of depression? Glover AT, Shaw SM, Williams SG, Fildes JE. Brain Behav Immun. 2010 Feb;24(2):173. doi: 10.1016/j.bbi.2009.11.008.

PMID 19689617 (2009)

The effect of beta-blockers on the adaptive immune system in chronic heart failure. Shaw SM, Coppinger T, Waywell C, Dunne L, Archer LD, Critchley WR, Yonan N, Fildes JE, Williams SG. Cardiovasc Ther. 2009 Fall;27(3):181-6. doi: 10.1111/j.1755-5922.2009.00089.x.

PMID 19643367 (2009)

Decreased immune responses to influenza vaccination in patients with heart failure. Shaw SM, Williams SG, Yonan N, Fildes JE. J Card Fail. 2009 Aug;15(6):549. doi: 10.1016/j.cardfail.2009.05.007.

PMID 19298913 (2009)

The immune system and chronic heart failure: is the heart in control? Fildes JE, Shaw SM, Yonan N, Williams SG. J Am Coll Cardiol. 2009 Mar 24;53(12):1013-20. doi: 10.1016/j.jacc.2008.11.046.

PMID 18812222 (2009)

BNP directly immunoregulates the innate immune system of cardiac transplant recipients in vitro. Shaw SM, Fildes JE, Puchałka CM, Basith M, Yonan N, Williams SG. Transpl Immunol. 2009 Jan;20(3):199-202. doi: 10.1016/j.trim.2008.08.010.

PMID 18572075 (2008)

Non-specific immunomodulation in chronic heart failure. Fildes JE, Shaw SM, Yonan N, Williams SG. Lancet. 2008 Jun 21;371(9630):2083. doi: 10.1016/S0140-6736(08)60913-7.

Reviews & Perspectives

PMID 31668141 (2019)

The future application of nanomedicine and biomimicry in plastic and reconstructive surgery. Amin K, Moscalu R, Imere A, Murphy R, Barr S, Tan Y, Wong R, Sorooshian P, Zhang F, Stone J, Fildes J, Reid A, Wong J. Nanomedicine (Lond). 2019 Oct;14(20):2679-2696. doi: 10.2217/nnm-2019-0119.

PMID 23257172 (2013)

Non-invasive approaches for the diagnosis of acute cardiac allograft rejection. Miller CA, Fildes JE, Ray SG, Doran H, Yonan N, Williams SG, Schmitt M. Heart. 2013 Apr;99(7):445-53. doi: 10.1136/heartjnl-2012-302759.

PMID 27059309 (2016)

A comprehensive review on learning curve associated problems in endoscopic vein harvesting and the requirement for a standardised training programme. Krishnamoorthy B, Critchley WR, Venkateswaran RV, Barnard J, Caress A, Fildes JE, Yonan N. J Cardiothorac Surg. 2016 Apr 8;11:45. doi:10.1186/s13019-016-0442-y.